Antietam Pharmacy was established in 1980 as a Medicine Shoppe by owner Albert Zitomer. In 1985 George Meckley, whose family was well known in Waynesboro as the owners of Antietam Dairy, purchased the pharmacy. At that time, David Riley began working part-time and when George was ready for semi-retirement, Dave purchased the pharmacy in 2005, re-naming it Antietam Pharmacy.